Manufacturing Equipment, Downstream Processing

Increases in efficiencies, flexibility, scalability, and sustainability are impacting adoption.

Purolite and Repligen have commercially launched a new CH1 affinity resin for the purification of specialized mAbs.

The 3M Harvest RC Chromatographic Clarifier, BT500 is the latest addition to the company’s chromatographic clarifier portfolio.

USP offers strategies to minimize residual impurities in downstream processing.

SCHOTT now offers ViewCell, a new component meant to add flexibility to biopharmaceutical process control.

The innovation of affinity ligands must take stability into consideration for present and future purification applications.

Innovations in downstream processing accelerate development, enhance efficiency, and promote sustainability.

CPC presents a green alternative to chromatography that supports sustainable operations.

CPC presents a green alternative to chromatography that supports sustainable operations.

In this article, a simple chromatographic model is proposed that is capable of predicting the impact of pH and ionic strength on HIC chromatograms.

SMB technology in the downstream can facilitate the shift to continuous bioprocessing.

Downstream processing will continue to see shifts with the incorporation of modern, efficient technologies.

Sartorius BIA Separations and Teknova will collaborate to combine their technologies in an effort to streamline the downstream purification process.

Single-use systems hold key benefits for biomanufacturers, despite certain limitations.

The testing of new convecdiff membranes shows this material to be well suited for lab- and commercial-scale bind-and-elute applications.

The design of viral clearance studies must keep pace with the quickly evolving biologic drugs industry.

Freudenberg Medical’s Heflix TPE tubing is a high purity TPE intended for bioprocessing applications.

A simplified downstream process can save time and costs but requires enabling technologies.

Merck has entered into a collaboration with Agilent Technologies with the aim of filling the industry gap in PAT for downstream processing.

The past year of downstream processing has brought innovations in pH sensitive antibody purification, single-use fermentation separators, and more.

Emerging drug classes are giving rise to challenges in downstream processing, pushing the need for strategizing efficiencies.

Innovations aid efficient processing.

Enhancement of resin technology can improve the ability of chromatography to purify the growing landscape of increasingly complex biomolecules.

Confounding signals pose challenges to analytical methods necessary for managing residual impurity removal in biotherapeutic manufacturing.

Process chromatography in downstream processing has seen steady improvements over the years, but there is still room for improvement.

BlackBerry’s QNX real-time operating system may create cybersecurity vulnerabilities, according to FDA.

Automation is one asset that benefits cell harvesting by cutting out laborious manual steps and minimizing contamination.

New biologic modalities, such as cell and gene therapies, pose increasing difficulties in viral clearance testing methods.

Recent innovations in chromatography resins offer promising advantage in downstream bioprocessing.

Sartorius has expanded in the United Kingdom with the relocation to a new facility in Havant, Hampshire, for downstream processing equipment.