Manufacturing, Cell Culture and Fermentation

A new defined coated cell cultureware by denovoMATRIX allow for the serum-free expansion of mesenchymal stem cells.

The partners will collaborate to identify the bioactive components in hydrolysates, which have long been used as additives in cell culture media and feed formulation in the biopharma industry.

Successful process intensification with inline dilution requires effective monitoring and control.

Recently released equipment and products include microbioreactor systems, cell therapy automation software, and IIoT-enabled flow sensors.

This article provides a review of various 2000-L single-use bioreactors used by biopharmaceutical suppliers for commercial production.

The new 40,000-ft2 facility will support Bayer's growing biologics portfolio in oncology, cardiology, and additional therapeutic areas.

The company has launched a comprehensive portfolio of custom cell biology solutions and a new cell-line engineering technology.

Single-use components for biopharmaceutical manufacturing have a lower environmental impact than reusable components, but disposal is still a consideration.

MilliporeSigma’s use of modified amino acids can simplify the fed-batch process in biomanufacturing.

Automation in cell-line development and cell culture is leading to more consistent quality while improving efficiency, and, ultimately, speed to market.

Advances in single-use technologies, sensors, and cell retention systems facilitate processes designed for the long run.

Under the new long-term agreement, Sartorius Stedim Biotech will continue to offer Lonza media and buffer products under non-exclusive terms.

This article will explore the requirements for media and supplements needed to maintain newer cell lines, such as those based on human cells and fungal cells.

New products were developed as next-generation process intensification technologies, MilliporeSigma reports.

A collaboration integrates Sartorius Stedim Biotech’s BIOSTAT STR bioreactors and Repligen’s XCell ATF cell-retention control technology to create simplified, scalable equipment for intensified cell culture.

Biopharma seeks alternatives that meet the needs for next-gen biologic drug production.

Late-stage and commercial biomanufacturing pose a challenge to cell-culture processing.

Higher cell titers and cell densities have posed a challenge to cell harvesting, a crucial step in biologics manufacturing.

Transcriptomics plays a role in influencing the production of recombinant therapeutics in microbial and mammalian hosts.

The company is increasing its cell culture media production capacity at its facilities in Pasching, Austria, and Logan, Utah.

The new platform is expected to speed up cell line development.

Fujifilm acquires cell culture media companies Irvine Scientific Sales Company and IS Japan.

Sartorius Stedim Biotech has launched a new automated parallel bioreactor system for perfusion culture.

Modeling at various stages of the data analytics continuum aids scale comparison of a bioreactor.

The study suggests that circumventing evolution in cell factories can enable the commercialization of new biobased chemicals to large-scale.

Corning will feature its 3D bioprinting technology and tools to support 3D cell culture at booth #1029 during the SLAS 2018 conference on Feb. 3-7, 2018 in San Diego, CA.

Comecar will provide cell culture equipment for biopharmaceutical company CO.DON AG's new production site in Leipzig, Germany.

Recent investments show expansion activity in cell culture facilities.

BioTek Instruments has released a second edition of its BioSpa software that now offers users a simplified but effective interface for kinetic imaging or detection workflows.

Gilead Sciences will acquire Cell Design Labs to further cell-therapy research and development efforts.