Considerations During Development of a Protein A-Based Antibody Purification Process
Publication
Article
BioPharm InternationalBioPharm International-01-01-2002
Volume 15
Issue 1
by Harish Iyer, Felicia Henderson, Eric Cunningham, James Welbb, John Hanson, Christopher Bork, and Lynn Conley, IDEC Pharmaceuticals Corporation Scale-up changes in an antibody purification process can increase final product purity, make the process more robust, and reduce processing time. This case study focuses on the initial purification step -- protein A chromatography -- and offers data collected from several years of process development work on many different antibodies.
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Systematic Troubleshooting for LC/MS/MS: Part 2, Large-Scale LC/MS/MS and Automation
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Considerations During Development of a Protein A-Based Antibody Purification Process
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