Webinar Date/Time: Session 1: Tues, Dec 5, 2024, at 12:00 PM BST | 1:00 PM CET Session 2: Tues, Dec 5, 2024, at 11:00 AM PST | 2:00 PM EST | 7:00 PM GMT Session 3: Wed, Dec 6, 2024, at 9:30 AM IST | 12:00 PM SGT | 1:00 PM JST | 3:00 PM AEDT
Webinar Date/Time: Thu, Nov 7, 2024 11:00 AM EDT
Explore how an integrated, single platform imaged capillary isoelectric focusing (icIEF)-UV/MS workflow with the Intabio ZT system aims to tackle the challenge of charge heterogeneity profiling with a disruptive strategy that allows for separation, quantitation, and identification of individual charge variants to be achieved in minutes on a single platform.
Webinar Date/Time: Wed, Jul 24, 2024 12:00 PM EDT
Charge heterogeneity is present in most biopharmaceutical protein products. During the manufacturing process, charge heterogeneity of the protein therapeutics can occur due to enzymatic cleavage and chemical post-translational modifications (PTM). For therapeutics like ADCs, not only the antibody contributes to the heterogeneity but also the linker and payload, which add even more complexity to the charge variant profiles. Characterizing the charge heterogeneity of ADCs is essential for critical quality attribute (CQA) assessment to ensure drug safety, efficacy, and potency.
Webinar Date/Time: Tue, May 21, 2024 11:00 AM EDT
Webinar Date/Time: Thu, Mar 28, 2024 11:00 AM EDT
Earlier assessment of molecules provides valuable insights into the manufacturing developability of molecules, reducing the need for unnecessary experimentation. The Intabio ZT system has the potential to make in-depth characterization of biopharmaceutical product charge variants quicker and more efficient to meet demanding timelines during early-phase clinical development.
Webinar Date/Time: Thu, Feb 8, 2024 11:00 AM EST
Webinar Date/Time: Thu, Sep 14, 2023 11:00 AM EDT