SCIEX

Webinar Date/Time: Session 1: Tues, Dec 5, 2024, at 12:00 PM BST | 1:00 PM CET Session 2: Tues, Dec 5, 2024, at 11:00 AM PST | 2:00 PM EST | 7:00 PM GMT Session 3: Wed, Dec 6, 2024, at 9:30 AM IST | 12:00 PM SGT | 1:00 PM JST | 3:00 PM AEDT

Webinar Date/Time: Thu, Nov 7, 2024 11:00 AM EDT

Explore how an integrated, single platform imaged capillary isoelectric focusing (icIEF)-UV/MS workflow with the Intabio ZT system aims to tackle the challenge of charge heterogeneity profiling with a disruptive strategy that allows for separation, quantitation, and identification of individual charge variants to be achieved in minutes on a single platform.

Webinar Date/Time: Wed, Jul 24, 2024 12:00 PM EDT

Charge heterogeneity is present in most biopharmaceutical protein products. During the manufacturing process, charge heterogeneity of the protein therapeutics can occur due to enzymatic cleavage and chemical post-translational modifications (PTM). For therapeutics like ADCs, not only the antibody contributes to the heterogeneity but also the linker and payload, which add even more complexity to the charge variant profiles. Characterizing the charge heterogeneity of ADCs is essential for critical quality attribute (CQA) assessment to ensure drug safety, efficacy, and potency.

Webinar Date/Time: Tue, May 21, 2024 11:00 AM EDT

Webinar Date/Time: Thu, Mar 28, 2024 11:00 AM EDT

Earlier assessment of molecules provides valuable insights into the manufacturing developability of molecules, reducing the need for unnecessary experimentation. The Intabio ZT system has the potential to make in-depth characterization of biopharmaceutical product charge variants quicker and more efficient to meet demanding timelines during early-phase clinical development.

Webinar Date/Time: Thu, Feb 8, 2024 11:00 AM EST

Webinar Date/Time: Thu, Sep 14, 2023 11:00 AM EDT

Webinar Date/Time: Tue, Aug 15, 2023 11:00 AM EDT

Webinar Date/Time: Tue, Aug 1, 2023 11:00 AM EDT

Rapid sample analysis using AEMS technology improves bioanalytical study turnaround

Webinar Date/Time: Tue, Aug 29, 2023 11:00 AM EDT

This application notes demonstrates the long-term reproducibility and performance of the SCIEX 7500 system with challenging matrices..

This technical note demonstrates the comprehensive characterization and confident identification of glucuronide metabolites from hepatocyte incubations of midazolam.

Webinar Date/Time: Wed, May 3, 2023 11:00 AM EDT

Wednesday, October 6, 2021 at 12pm EDT | 9am PDT | 5pm BST | 6pm CEST In this webinar, you will learn about the possibility of GMP method transfer for HCP assays leveraging a robust and automated workflow based on combining data-dependent and data-independent mass spectrometry. A study of data from multiple projects over three years demonstrated the robustness and reproducibility of the method.

*Live Date: Tuesday, March 2, 2021 at 11am EST | 8am PST | 4pm GMT | 5pm CET* In this webinar, you will learn how LC-MS has been broadly leveraged to accelerate the development of antibody-drug conjugates (ADCs). *Available On Demand Until March 2, 2022*

***Live: Wednesday, January 20, 2021 at 11am EST | 8am PST | 4 pm GMT | 5pm CET *** Cell culture media (CCM) optimization is a critical step during the development and scale up of biotherapeutic manufacturing process. In particular, the emphasis on quality by design has made it necessary to understand how the components of CCM change during production and how these changes relate to product quality. In this webcast, learn how targeted cell-culture media workflow can help scientists understand growth media for biotherapeutics and improve their manufacturing process. ***On demand available after final airing until Jan. 20, 2022***

***Live: Tuesday, November 3, 2020 at 11am EST| 8am PST| 4pm GMT| 5pm CET*** In this webcast, learn how multi-attribute assays were used to accelerate routine workflows for biotherapeutics characterization at the intact and subunit level. This new streamlined approach increased the efficiency to perform stability assessment of antibody-drug onjugates (ADC) significantly.***On demand available after final airing until Nov. 3, 2021***

The increase in non-monoclonal antibody protein drug candidates has required researchers to develop new methods. By adapting existing approaches find out how Dr. Stephen Lock is answering this challenge to better profile these extremely complex proteins. Wednesday, Sept. 2, 2020 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST On demand available after final airing until Sept. 2, 2021.