Yoshiaki Miko

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Yoshiaki Miko is Associate Director of Biologics & New Modalities Development, Pharmaceutical Sciences, Takeda Pharmaceutical.

Articles

Nikolai Sorokin/Stock.adobe.com - concept illustrating a needle that can cause pinholes

Proposing a New Method of Detecting Pinholes in Single-Use

Toshihiko Otsubo;Shinji Tsuji;Yoshiaki Miko;Tetsuya Moritake;Osamu Shirokizawa;Takashi Kaminagayoshi
September 2nd 2020

The increased use of single-use bags in biologic manufacturing poses the risk of pinholes and other defects that cannot currently be tested for.

BP1116_CleanValProtein_Figure-10.jpg

Development of a Technique for Quantifying Protein Degradation

Xi (Dylan) Wang;Takashi Kaminagayoshi;Tomohiro Doi;Kosuke Takenaka;Yoshiaki Miko;Osamu Shirokizawa;
November 1st 2017

This article demonstrates that a modified SDS–PAGE can be easily used as a tool for quantifying the degree of protein degradation.

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