Timothy Diehl

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Scientist of Purification Process Development at Medarex

Articles

Precipitation of Process-Derived Impurities in Non-Protein A Purification Schemes for Antibodies

Xiao-Ping Dai, PhD;Jue (Michelle) Wang, PhD;Deena Aguiar;Timothy Diehl;Alahari Arunakumari, PhD

October 2nd 2009

Precipitation prior to capture chromatography offers a simple, robust, and economical method to remove CHO host cell proteins and DNA.

Optimizing the Primary Recovery Step in Nonaffinity Purification Schemes for HuMAbs

Jue (Michelle) Wang, PhD;Deborah Perkins;Deena Aguiar;Mark Watkins-Fischl;Timothy Diehl;Alahari Arunakumari, PhD

An alternative approach to traditional Protein A schemes is comparable in overall efficiency, product recovery, and quality.

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