Eduardo MartÃnez, PhD, is the head of the development division at the Center for Genetic Engineering and Biotechnology
Scale up of Fed-Batch Culture to Produce Plasmid DNA in Escherichia coli (Peer Reviewed)
The authors present scale-up from a 5-L fermentor to a 50-L pilot-scale using the criterion of constant power consumption per unit liquid volume.
High-Cell-Density Culture to Produce Plasmid DNA for Gene Therapy in E. coli
How to produce Plasmid DNA in a high-cell-density culture.