ISPE Facility of the Year Awards Recognize Innovative Biologic Manufacturing Facility Designs
The ISPE FOYA 2020 category awards included biologics facilities.
Several biologics facilities were announced as category winners in the annual Facility of the Year Awards (FOYA) program of the International Society for Pharmaceutical Engineering (ISPE) (1).
Bristol-Myers Squibb won the Project Execution Category award for its Multi-Product Cell Culture (MPCC) Project in Cruiserath, County Dublin, Ireland. The project transformed and expanded an existing API site into a biologics drug substance manufacturing campus (1).
Architecture, engineering, construction management, and turnover services for the project were provided by Jacobs (2). The facility is designed as a flexible, multi-product manufacturing operation and is now in commercial operation, having recently received regulatory approval from both FDA and the European Medicines Authority (2).
Pfizer won the Facility Integration Category for its clinical manufacturing facility in Andover, MA. The project relocated clinical-scale capacity from Missouri to Massachusetts in order to expand clinical biological drug substance manufacturing capacity and to vertically integrate by co-locating early-phase clinical manufacturing with the site’s existing large-scale commercial manufacturing (1).
Sanofi was awarded the Facility of the Future Category award for its Sanofi Digitally Enabled Integrated Continuous Biomanufacturing Facility in Framingham, MA. The facility uses single-use systems for its continuous upstream and downstream processing and buffer and media preparation and distribution. Digital integration includes process control, data collection, and analytics. Fully electronic batch records enable review and release by exception (1).
References
1. ISPE, “2020 ISPE Facility of the Year Awards Winners Announced,” Press Release, April 7, 2020.
2. Jacobs, “Jacobs’ Designed and Built, Multi-Product Cell Culture (MPCC) Facility Wins International Society for Pharmaceutical Engineering ‘Facility of the Year Award’,” Press Release, June 24, 2020.
