DO Control PID Tuning for Cell Culture Applications
The proportional–integral–derivative (PID) control mechanism is used for a variety of processes, including dissolved oxygen (DO) control. This protocol introduces a method developed to optimize the PI values on Eppendorf bioprocess controllers.
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Glycan analysis provides key information on critical quality attributes that could affect stability, safety and efficacy of a protein therapeutic. Specific needs for understanding the glycosylation profiles change throughout the drug development process, but the requirement for high-resolution glycan information remains the same and is essential to help ensure product quality.
