Development of an In Situ Spectroscopic Method for Cleaning Validation using Mid-IR Fiber-Optics

Publication
Article
BioPharm InternationalBioPharm International-05-01-2002
Volume 15
Issue 5

by Narinder K. Mehta, Javier Goenaga-Polo, Samuel P. Hernandez-Rivera, David Hernandez, Peter J. Melling, and Mary A. Thomson, Remspec Corporation A fiber-optic, mid-IR spectroscopy probe combined with a grazing-angle reflectance sampling head can be used as a solvent-free in situ method for validating cleanliness with substantial improvement in accuracy.

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