DepoVax Technology Selected for HPV–related Cancer Trials
Immunovaccine's vaccine technology chosen for cervical, head, and neck cancer trials conducted by Dana-Farber Institute.
Dana-Farber has been awarded a research grant of $1.2 million for clinical evaluation of its cancer vaccine. The grant from Stand Up To Cancer and the Farrah Fawcett Foundation was awarded to a team of Dana-Farber researchers at the 2014 American Association for Cancer Research annual meeting. The three-year grant will be used to fund a Phase I clinical trial of the group’s peptide cancer antigen formulated in DepoVax in patients with HPV-related cervical, head, and neck cancers.
The grant was awarded based on a proposal highlighting the potential of Dana-Farber’s proposed cancer antigen identified by a new mass spectrometry method termed Poisson detection MS and Immunovaccine’s DepoVax platform. The DepoVax data focused on clinical trial results with DPX-Survivac, which demonstrated strong immune response activity in cancer patients and the immune enhancement observed with the immune modulating agent cyclophosphamide. Dana-Farber’s proposed Phase I study in HPV-related cancers will use the same approach, formulating the Institute'speptide-based vaccine in DepoVax and administering it to patients in combination with cyclophosphamide.
Source: Immunovaccine
Texas' MD Anderson Cancer Center Creates New Cell Therapy Institute
November 11th 2024With the launch of the Institute for Cell Therapy Discovery and Innovation, the MD Anderson Cancer Center will bring together expertise in developing cell therapies for cancer, autoimmune diseases, and infections.
