DCAT Week 2025: A Review of Key Innovative Pharma Ingredients

Standout pharmaceutical ingredients in the past year have been those that logically address the pharmaceutical industry's biggest topics and biggest challenges, says Christine Mya-San, global account manager, Roquette Pharma Solutions, in an interview with BioPharm International® ahead of DCAT Week 2025, being held in New York City on March 17–20.

A good example of such ingredients are low nitrite excipients that support drug manufacturers and their ongoing mission to reduce the risk posed by nitrosamines, she points out. Roquette has worked to assess and certify its existing low-nitrite products to support reformulation efforts. In addition, the company is developing solutions to enhance medication adherence, such as β-cyclodextrin (Kleptose DC), which improves solubility and provides effective taste-masking, and mannitol (Pearlitol 200 GT), which offers enhanced compressibility and resistance to tablet capping, thus enabling the production of smaller, more convenient mini-tablets, Mya-San notes.

Looking ahead, Mya-San anticipates that pharmaceutical ingredients such as high-performance tablet coatings will optimize tablet manufacturing compared to traditional sugar coatings. "Recently, we put the spotlight on high-performance coatings, highlighting features such as low processing temperatures, which help in two-fold: first, for reduced energy usage, and second for that lowered nitrosamine formulation [risk]," she states.

Meanwhile, in terms of innovation, she highlights the potential of 3D drug printing and artificial intelligence to play a central role in the identification and large-scale production of new therapeutic ingredients. Three-dimensional printing, for example, could enable the printing of customized medicines tailored to individual patient needs, including the combination of multiple medications into a single dosage form.

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About the speaker

Christine Mya-San, Global Account Manager, Roquette Pharma Solutions

Christine Mya-San is a global account manager at Roquette Pharma Solutions. Her love of the sciences started as a Cancer Research Fellow at the National Institutes of Health. Post fellowship, she started working at Covance as a risk mitigation specialist and sales representative. Mya-San has worked at notable companies such as Sigma-Aldrich (Merck KGaA) and at Honeywell Research Chemicals. Previous roles at Roquette include Americas channel management and global market management for the over-the-counter and nutraceuticals markets. Mya-San received her Bachelor of Science in biology at Dickinson College (Carlisle, Penn.) and her Master of Business Administration from Saint Louis University.