Advances in mAb Purification with Super A Chromatography Resin

The highest DBC form Ab capture step with mild elution pH, low aggregate, low HCP and DNA are demonstrated using a newly developed Super protein A resin.

Register Free: https://www.biopharminternational.com/bp_w/chromatography-resin

Event Overview:

Technical data from a newly developed Super protein A resin shows that it can improve mAb purification process economy and robustness for the capture step. Experimental data demonstrates its alkaline stability is exceptionally good and allows effective CIP using a very high alkaline condition while still maintaining its highest dynamic binding capacity after many cycles. Data also shows that elution with high or milder pH condition can be achieved to reduce aggregation of the monomer eluate. Moreover, low HCP, low DNA, and low protein A leakage make polishing steps more effective.

Key Learning Objectives:

• Improve mAb capture step with an exceptionally alkaline stabile protein A resin.
• Enhance mAb monomer and its elution volume using a Super protein A resin.
• Improve mAb process purification economy and robustness.

Who Should Attend:

• Antibody purification scientists, managers, and directors
• Biopharma R&D scientists
• Biotherapeutics discovery scientists

Speaker:

Phu Duong, PhD
Senior Manager of Product Management – Americas
Tosoh Bioscience, LLC

Phu Duong, PhD, earned his degree in 2003 from Temple University, Philadelphia, Pennsylvania. He has held various roles in the marketing and technical service departments at Tosoh Bioscience. Currently, Dr Duong is leading product management (Americas) for all product lines. His expertise is in developing the strategy for the growth of the consumable and capital equipment portfolios and commercializing new products to support the biotherapeutics market.

Register Free: https://www.biopharminternational.com/bp_w/chromatography-resin