Adeno-associated Virus Production in Suspension Cell Culture Using the SciVario twin Bioprocess Controller
This application note demonstrates the feasibility of an efficient and scalable AAV production platform, using a suspension-adapted HEK293 cell line (Expi293F) as the host.
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Glycan analysis provides key information on critical quality attributes that could affect stability, safety and efficacy of a protein therapeutic. Specific needs for understanding the glycosylation profiles change throughout the drug development process, but the requirement for high-resolution glycan information remains the same and is essential to help ensure product quality.
