Optimizing microfluidic LNP formulations with in-line particle size and concentration measurements
November 17th 2022Thursday, November 17, 2022 Session 1: 8 am PST | 11 am EST | 5 pm CET Session 2: 10 am CET | 9 am GMT | 6 pm JST Session 3: 10am JST | 5 pm PST Learn how to automate LNP production with in-line particle size and concentration measurements using multi-angle light scattering (MALS) and dynamic light scattering (DLS).
Oligonucleotide Therapeutics: Chemistry and therapeutic modalities
November 3rd 2022Thursday, November 3, 2022 Session 1: 10 am CST | 11 am JST (APAC) Session 2: 1 pm GMT | 2 pm CET (EMEA) Session 3: 2 pm EST | 11 am PDT (Americas) (Americas)Register for our educational webinar series presented by Professor Tom Brown, University of Oxford and learn more about the advances in oligonucleotide therapeutics and diagnostics!
Intact Mass Analysis of Multispecific Antibodies: Automation and Data Management
October 25th 2022Tuesday, October 25th, 2022 at 11am EDT|8am PDT|4pm BST|5pm CEST Discover approaches for medium- and high-throughput analysis of multispecific antibodies using Byos software with AWS automation workflows. In this presentation, we will discuss how to use this data to select optimal therapeutic candidates produced on our high-throughput protein production platform.
New Developments in Mass Spectrometry-Based Single-Cell Proteomics
October 21st 2022Fri, Oct 21, 2022 11:00 AM EDT Learn how Karl Mechtler has developed an end-to-end workflow to efficiently prepare and analyze samples for single-cell proteomics by mass spectrometry. This workflow enables direct injection of single cells to identify approximately 1,500 protein groups per analytical run and uncover the surprising heterogeneity of cell populations.
Novel Oligonucleotide Sample Clean-up and Method Optimizations
October 19th 2022Wednesday, October 19th 2022, 11am EDT | 8am PDT | 4pm BST | 5pm CEST In this webinar, we will give an overview of sample preparation and LC-MS strategies for synthetic oligonucleotides, including how to adjust experimental design depending on the oligo and sample matrix. Additionally, novel small volume clean-up solutions for oligonucleotides will be explored to further optimize challenging methods.
Translate your idea into product: AI-driven antibody discovery at Evotec
October 18th 2022October 18, 2022, 2pm EDT Evotec recently hosted its Innovation Week webinar series - 5 virtual sessions over 5 days. Session 5 discusses Evotec’s capabilities for supporting all activities across the R&D continuum for biotherapeutics, i.e. Discovery and optimization of novel antibodies for specific disease targets, evaluation of lead antibodies for disease efficacy and safety, alongside process development and manufacturing
How to Find Success with Lentiviral Production Using Fixed Bed Bioreactor Technology
October 17th 2022Monday, October 17, 2022 at 11am EDT | 4pm BST | 5pm CEST Why would a CDMO to leverage fixed-bed bioreactor technology to develop and produce GMP lentiviral vectors? Join us for a discussion on increasing quality and decreasing time and cost to accelerate time to clinic and market for lentiviral products with technology.
Best Practices in HCP Assay Development and Integration of Advanced Orthogonal Methods
October 11th 2022Tuesday, October 11, 2022 at 11 AM EDT Learn about best practices in Host Cell Protein (HCP) assay development and qualification. Improve your understanding of the advanced orthogonal methods used to fully characterize HCPs in your process
Characterization of Biotherapeutic Beasts by Mass Spectrometry
September 29th 2022Thursday, September 29, 2022 at 7am PT | 10am ET | 4pm CET Novel methods have been developed and applied on Biotherapeutics Beasts in the half Megadalton to 3-4 MDa range to measure AAV Full:Empty genome ratio using charge detection mass spectrometry on the Q Exactive UHMR mass spectrometer with Direct Mass Technology mode.
Preparing biologics for commercialization: strategies to reduce risk and optimize outcomes
September 28th 2022Wednesday, September 28, 2022 at 10 AM EST | 4 PM CET Optimize your late-phase strategy to prepare your biologic for commercialization. CDMO experts share their time-tested best practices on how to adapt for uncertain market demand to get your drug to market on time.
Automated High Throughput SEC Native Mass Spectrometry for mAb Screening
September 22nd 2022Thursday, September 22nd, 2022 9:00am EDT|6:00am PDT|2:00pm BST|3:00pm CEST 2:00pm EDT|11:00am PDT|7:00pm BST|8:00pm CEST See how RapidFire automated size exclusion chromatography (SEC) combined with the power of ion mobility mass spectrometry (IM-MS) enables efficient biotherapeutic development.
Advantages of a One-Stop Shop for Freeze/Thaw And Cold-Chain Process Development
September 21st 2022Wed, Sep 21, 2022 2:00 PM EDT This webinar will review the key considerations and gaps in evaluating freeze/thaw solutions, examine the elements of a dedicated technology center to bridging these gaps and development risks, and explore successful case studies of a technology center optimizing processes and speed-to-market.
Innovation Standardized – High Performance Surface Consumables for Bioseparation
September 20th 2022Tuesday, September 20, 2022 at 11 AM EST During chromatographic analysis of complex biotherapeutics, analytes may contain electron-rich functional groups, which have an affinity to metal surfaces and may cause issues such as poor peak shape. Join our webinar to learn how Waters addresses these challenges.
Stem Cell Derived Exosome Production in Stirred-Tank Bioreactors
September 15th 2022Thursday, September 15th, 2022 at 4pm CEST | 3pm BST | 10am EDT Extra cellular vesicles and especially exosomes have recently gained favor for therapeutic medicine development due to possessing structures that can be modified to conveniently deliver payloads, such as specific proteins, genetic lipids, and genetic materials including messenger RNA (mRNA, and genomic DNA (gDNA) from their progenitor cell. Most recently, there is increasing interest in the therapeutic potential of exosomes produced by Mesenchymal Stem Cells (MSCs). Stirred-tank bioreactors offer the possibility to tightly control and monitor the production of exosomes, as well as the scalability, to produce increasing amounts. However, the cultivation of stem cells in stirred-tank bioreactors requires profound knowledge and precise control of the process.
Tools for the Analysis of New Biotherapeutic Drug Modalities: A sponsored virtual symposium
September 14th 2022Wednesday, September 14, 2022 Morning Session: 9am EDT | 6am PDT | 2pm BST| 3pm CEST Afternoon Session: 1pm EDT | 10am PDT | 6pm BST | 7pm CEST Are your analytical methods keeping up with the pace of new biotherapeutic drug modalities? Attend this symposium to ensure success!
Leveraging Data for Predictive & Real-time Bioprocess Performance Improvements
September 8th 2022Thu, Sep 8, 2022 11am EST | 8am PST | 4pm BST | 5pm CEST Digitalization & leveraging real-time data are key for biopharma process improvement. Insilico models and soft-sensors boost biopharma performance to unprecedented levels.