Automated Data Processing Workflows for Targeted Peptide Mapping Data Analysis and Reporting

Discover how scientists at Janssen are leveraging customized system integration and data processing.

Register Free: https://www.biopharminternational.com/bp_w/targeted-peptide

Event Overview:

Mass spectrometry (MS)-based characterization of therapeutic proteins yields product-specific data that are leveraged throughout development to assist science and risk-based decision-making. MS-based targeted peptide mapping is a foundational technique for biotherapeutic characterization and allows relative quantitation of site-specific post-translational modifications that can be used, for instance, to assess product quality.

Recent advancements such as automated sample preparation and data acquisition have improved the overall efficiency of MS-based peptide mapping methodology. However, analysis review and reporting of the targeted peptide mapping data remains a significant bottleneck. This webinar highlights the development of automated workflows in Genedata Expressionist for targeted analysis and reporting of MS-based peptide mapping data.

The newly developed integration and processing capabilities automate several key data processing steps, which includes retrieval of sample metadata from an independent database, analysis of MS-based peptide mapping data, updates to historical MS data libraries for improved workflow performance, and export of standardized reports for subsequent large-scale data aggregation.
Discover how scientists at Janssen are leveraging customized system integration and data processing to:

• Automate targeted MS-based peptide mapping of protein therapeutic samples
• Drive workflow processes using sample-specific metadata
• Standardize data reporting to enable meaningful data aggregation

Key Learning Objectives

• Learn how automated peptide mapping workflows reduce variability and improve confidence in results.
• See how sample metadata can be utilized to drive sample-specific data processing and analysis.
• Discover how standardized reporting enables meaningful data aggregation.

Who Should Attend

• Biopharma analytical scientists, lab heads, and directors who are looking to automate targeted mass spectrometry-based peptide mapping workflows for characterization and quality monitoring of biotherapeutics

Speaker

Michael E. Pettit
Scientist
Janssen Research & Development
Malvern, PA, USA

Michael E. Pettit is a Scientist at Janssen Research & Development, based in Malvern, PA, USA. Michael gained a Ph.D. from Baylor University in 2018 and subsequently served as a National Research Council Postdoctoral Research Associate for the National Institute of Standards & Technology from 2018 to 2019. An expert in mass spectrometry-based proteomics, Michael has worked on the MS-based characterization of biotherapeutics at Janssen since 2020. His current research focuses on forced degradation studies, including development of mass spectrometry-based methods and data collection strategies for enhanced characterization of biologically relevant peptides and proteins. Michael has special interests in workflow automation, data-aggregation, and artificial intelligence.

Register Free: https://www.biopharminternational.com/bp_w/targeted-peptide