Modeling the Efficacy of HTST for Inactivating Mouse Minute Virus
The authors investigate the sufficiency of high-temperature short-time treatment in inactivate mouse minute virus contamination.
Continuous Processing for the Production of Biopharmaceuticals
The authors review the technologies that may help bioprocessing become a truly continuous operation and present case studies that could contribute to the integration of upstream and downstream platforms.
Integrating Technology Transfer and Facilities Startup for Biologics
Careful planning, adequate staffing levels, and experienced project managers can help avoid pitfalls of transferring processes from one facility to another.
Essentials in Bioassay Design and Relative Potency Determination
The author describes common components of a relative potency bioassay and provides a framework for assay development, calculation, and control.
Lessons Learned Accelerate Vaccine Development
Collaboration and single-use technologies aided the rapid scale-up of Ebola vaccine manufacturing
A Review of the Challenges of Delivering Macromolecule Biologicals
Selecting a delivery method early on may be beneficial.
Platform Approach Speeds Process Development
A modular cell-culture platform demonstrates accelerated process development.
Behind the Scenes in Vaccine Development
Proven science-based strategies can help to accelerate vaccine development.
Size-Exclusion Chromatography for Preparative Purification of Biomolecules
The authors provide application data to support the use of SEC beyond small-scale operations.
Vaccine Development Faces Urgency and Challenges
Global outbreaks energize vaccine R&D and drive production modernization.
CMC Development is Hot
Demand is driving expansion and consolidation of formulation and clinical trial materials services.
The Importance of Buffers in Downstream Processing
Industry experts provide insights on the challenges and importance of using buffers in downstream processing.
BioPharm International, April 2016 Issue (PDF)
Click the title above to open the BioPharm International April 2016 issue in an interactive PDF format.
