Effects of Buffer Composition when using Mixed-Mode Chromatography
March 23rd 2020Multiple separation steps are often required to eliminate product- and process-related impurities impacting biopharmaceuticals. This study shows that buffer composition has an effect on target purity and recovery when using Nuvia aPrime 4A, a mixed-mode resin.
Using Digital MFC Capabilities to Improve Bioprocessing Results
March 23rd 2020This new white paper from Brooks Instrument describes the inner workings of digital MFCs and their ability to gather, generate and communicate a range of process data. The content reviews ways to utilize MFC device data to improve process control, system uptime, diagnostics, preventive maintenance and bioprocessing yields.
Challenging Microbial Sanitization of a Liquid Chromatography System
February 25th 2020To ensure that no contaminating or hazardous residual components remain after protein purification during biologic development, additional sanitization steps may be required for the instrumentation utilized during these processes.
Using Digital MFC Capabilities to Improve Bioprocessing Results
February 25th 2020This new white paper from Brooks Instrument describes the inner workings of digital MFCs and their ability to gather, generate and communicate a range of process data. The content reviews ways to utilize MFC device data to improve process control, system uptime, diagnostics, preventive maintenance and bioprocessing yields.