Integrated Analytical Platform Accelerates CMC Bioconjugate Development
Webinar Date/Time: Thursday, December 5th, 2024 at 11:00 AM EST
Overcome Bioconjugate Development Challenges and Accelerate CMC Timelines.
Register Free: https://www.biopharminternational.com/bp_w/bioconjugate-development
Event Overview:
The bioconjugate field is undergoing rapid evolution, and the development of new bioconjugate structures requires intricate, multifaceted approaches that encompass carrier molecules, linkers, and small molecule drugs. This complexity presents significant challenges in the analytical development of bioconjugates, including the need to assess linker-payload stability, conjugation heterogeneity (in terms of site and ratio), and process-related impurities, as well as to develop specialized assays to monitor the conjugation process. Moreover, a critical aspect is the efficient development of analytical methods tailored to the diversity of bioconjugates.
This presentation delves into the development of physicochemical and biochemical analysis methods for various types of bioconjugates, presenting an integrated analytical strategy to address development hurdles and accelerate the CMC timeline.
Key Learning Objectives:
- The critical quality attributes (CQAs) to monitor during process development
- Case studies for various physicochemical and biochemical methods
- Mass spectrometry application in PD support and product characterization
- WuXi XDC’s integrated analytical platform for bioconjugate CMC development
Who Should Attend:
- Analytical Scientists
- ADC/Bioconjugate Developers
- CMC Experts
- Quality Control Experts
- Laboratory managers interested in analytical innovations
Speaker:
Dr. Zhiguo Li
Executive Director
WuXi XDC
Dr. Zhiguo Li has 16+ years of biopharmaceutical industry experience in analytical chemistry and pharmaceutical science, including 9+ years at WuXi XDC and WuXi Biologics, 3 years at Novo Nordisk, and 2+ years at Abbott. He received his Bachelor’s Degree from Shandong University and Ph.D. from University of the Pacific, California.
Register Free: https://www.biopharminternational.com/bp_w/bioconjugate-development
