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Orjana Terova
Articles
Improving Aggregate Removal to Enhance Clinical Manufacturing of MAbs
Hydrophobic interaction chromatography (HIC) in flow-through mode offers a more efficient and cost-effective polishing/purification process to remove monoclonal antibody aggregates while maintaining purity at ≥99% than a mixed-mode bind/elute procedure.
Affinity Chromatography Accelerates Viral Vector Purification for Gene Therapies
A case study demonstrates that affinity chromatography can offer efficiency and scalability for gene therapy manufacturing using viral vectors.