John J. Li is technical application scientist III at Thermo Fisher Scientific.
Improving Aggregate Removal to Enhance Clinical Manufacturing of MAbs
September 28th 2018Hydrophobic interaction chromatography (HIC) in flow-through mode offers a more efficient and cost-effective polishing/purification process to remove monoclonal antibody aggregates while maintaining purity at ≥99% than a mixed-mode bind/elute procedure.