by Naidong Weng and Timothy D.J. Halls Covance Laboratories, Inc. LC/MS/MS provides superior sensitivity and selectivity, rapid analysis, maximized development efficiencies, and improved turnaround times. Although large-scale LC/MS/MS analysis is fraught with challenges, you can learn to overcome the obstacles with careful planning and these troubleshooting techniques. Part 1 presents troubleshooting techniques related to sample preparation and chromatography.
Mastering Antibody-Drug Conjugates
December 19th 2024In this episode, we explore BIOVECTRA’s capabilities in antibody-drug conjugate (ADC) manufacturing, from complex conjugation chemistry to synthesis of highly potent payloads. We’ll also showcase how BIOVECTRA’s extensive experience in complex chemistries and specialized small molecule manufacturing gives them a unique perspective, strengthening their approach to ADC production and ensuring clients receive custom solutions across all project stages.
Filter Sizing for Process Optimization in Life Sciences Sterile Filtration
April 24th 2025Bench-scale filterability studies play a critical role in optimizing sterile filtration in biopharmaceutical manufacturing. By guiding the selection and sizing of filters, these studies help streamline processes, improve scalability, and reduce costs. Through data-driven case studies, this paper highlights how the strategic use of pre-filters and membrane materials can maximize throughput and minimize filter fouling.