In this peer-reviewed article, the authors present a series of experimental studies showcasing the performance of MMS in secondary-structure biopharma characterization and compare it with conventional FTIR data.
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Microfluidic modulation spectroscopy (MMS) is a novel automated infrared spectroscopic technique with high sensitivity and repeatability. Here, the authors present a series of experimental studies showcasing the performance of MMS in the secondary structure characterization of biopharmaceutical products and compare the MMS results with the conventional Fourier transform infrared data.
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Submitted: Dec. 9, 2019
Accepted: March 9, 2020
Dipanwita Batabyal*, dbatabya@amgen.com, is scientist at Attribute Sciences-Higher Order Structure Group, Amgen, and Mats Wikström*, matsw@amgen.com, is principal scientist at Higher Order Structure, BR&C, Attribute Sciences, Amgen. Libo Wang is principal application scientist and Jeffrey Zonderman is chief commercial officer at RedShift Bioanalytics.
*To whom correspondence should be addressed.
BioPharm International
Vol. 33, No. 5
May 2020
Pages: 42–47
When referring to this article, please cite it as F. Mirasol, “Shaping IR Spectroscopy into a Powerful Tool for Biopharma Characterizations,” BioPharm International 33 (5) 2020.