Irvine Scientific Launches BalanCD HEK293 System for Large-Scale Expression of Proteins and Viral Vectors

Irvine Scientific, a company specializing in the optimization and manufacture of cell culture media has launched a new system, BalanCD HEK293 System, which has a versatile series of chemically-defined media, designed to increase productivity and deliver high yields of viral vectors and recombinant proteins.

According to Irvine Scientific, the BalanCD HEK293 System is fully scalable, and supports small to industrial scale batch sizes. The system uses human embryonic kidney (HEK293) cells and can support applications including viral vector production for gene therapy, transient gene expression, and recombinant protein production in suspension-adapted HEK293 cells.

BalanCD HEK293 growth and feed media have been designed to be chemically-defined and free of animal components, so that it saves time and cost in downstream processing, as well as meets regulatory requirements. The BalanCD HEK293 bi-functional medium supports both growth and transfection in multiple 293 cell lines, eliminating the need to change media before and after transfection. Complementing it is the BalanCD HEK293 Feed, which has been designed to support high-density cell growth to maximize production of recombinant proteins.

Anti-clumping supplement further increases productivity by preventing the natural tendency of HEK293 to aggregate, thereby, improving growth. Anti-clumping supplement is also animal-component-free and enzyme-free.

All products are manufactured in state-of-the-art cGMP facilities using strict raw material controls. Drug master files have been submitted to FDA.

Source: Irvine Scientific