St John Skilton, PhD

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St John Skilton, PhD, is the senior marketing manager at Waters Corporation.

Articles

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Capturing Conformational Changes in Biotherapeutics by Hydrogen Deuterium Exchange and UHPLC–MS

St John Skilton, PhD;Joomi Ahn
August 2nd 2010

By providing information on the relative accessibility of locations within a protein, HDX by mass spectrometry opens new windows into the higher order structure of biomolecules.

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Rapid Assessment of Molecular Similarity between a Candidate Biosimilar and an Innovator Monoclonal Antibody Using Complementary LC–MS Methods

Martin Gilar, PhD;Weibin Chen, PhD;Deepalakshmi P. Dakshinamoorthy;Asish Chakraborty, PhD;St John Skilton, PhD;Ying Qing Yu, PhD;Hongwei Xie, PhD;Joomi Ahn
August 2nd 2010

Intact protein LC–MS detected a mass variance of 62 Da and peptide mapping located a difference of two amino acids.

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