Rozaleen Dash is a post-doctoral fellow in the Department of Chemical Engineering at the Indian Institute of Technology (Delhi).
Mathematical Modeling of Cell-based Potency Data for mAb Biotherapeutics
A novel mathematical approach for fitting concentration-response curves is proposed that offers a more accurate estimation of potency data.
Late-Stage Failures of Monoclonal Antibodies
The authors review some of the monoclonal antibody candidates that reached Phase III clinical trials but were discontinued at later stages.
Late-Stage Failures of Monoclonal Antibody Biotherapeutics
Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars
A major advantage of SPR-based analysis is its ability to estimate the association and dissociation rate constants, an advancement over the traditional steady-state analysis of biomolecules.