Matteo D. Costioli is a bioprocess and innovation downstream process specialist at the Center of Expertise, Merck Serono SA
Safe Freeze–Thaw of Protein Drug Products: A QbD Approach
Apply a DoE strategy to test several formulations in parallel.
Cost of Goods Modeling and Quality by Design for Developing Cost-Effective Processes
Combine cost analyses with QbD to improve operations and lower costs.