Distek, Inc

The BIOne 10L SUB is highly innovative with expanded processing capabilities, ideal for scale-down modeling, material generation, and process optimization.

Accelerate process development with a customizable, liner-based, BIOne single-use solution.

Homogeneous environments are essential for successful bioprocesses. Using a benchtop model, we characterized system mixing dynamics and demonstrated the potential of power input and flow direction to effect system homogeneity.

Distek has earned a place on the modern bioprocessing laboratory benchtop with the BIOne Single-Use Bioreactor and BIOne 1250 Bioprocess Control Stations.

Accelerate your upstream process development

In this work we demonstrate the effectiveness of Design of Experiment methodology for upstream process development through the execution of transient gene expression optimization and oxygen mass transfer characterization studies.

It can be challenging to define suitable operational definitions for volume-dependent parameters for upstream bioprocesses. In this work, we perform robust DoE mass-transfer characterization of the BIOne SUB and utilize a kʟa criterion to successfully define such parameters for a HEK-293 process.