Waters Podcast #4: Why Ion Mobility is Shaping the Future
UPLC, QTof, HDMS, and more: A practical guide to the hottest techniques driving the future of biopharmaceutical science
As firms increasingly invest in biopharmaceutical development, there is a widespread need to educate scientists in new technologies and approaches in this rapidly evolving industry. For maximum effectiveness in drug development, the application of new techniques can save time and development costs. In this podcast series, we’ll provide you with a firm knowledge of the latest technological innovations in LC and LC/MS that have been designed to address and advance the very specific needs of the many applications areas in the biopharmaceutical laboratory.
Through a variety of topics highlighting our latest scientific work, this series will help you gain a better understanding of key bio-focused LC, MS, and software advancements. Learn how these solutions have been adopted by industry leaders around the world and how easy it is to implement the tools that deliver faster, better answers relating to the character and quality of your biopharmaceuticals.
Ion Mobility Separation (IMS) is a technique that has existed for more than two decades but only became commercially available with the launch of the Synapt™ systems from Waters in 2006. The implementation of IMS within an existing well-established instrument architecture meant that it has been easy to adopt, operate and to interpret the data. This podcast will show how IMS has enabled studies of protein conformation, pegylated proteins, top-down sequencing and characterization of protein glycosylation.
Mastering Antibody-Drug Conjugates
December 19th 2024In this episode, we explore BIOVECTRA’s capabilities in antibody-drug conjugate (ADC) manufacturing, from complex conjugation chemistry to synthesis of highly potent payloads. We’ll also showcase how BIOVECTRA’s extensive experience in complex chemistries and specialized small molecule manufacturing gives them a unique perspective, strengthening their approach to ADC production and ensuring clients receive custom solutions across all project stages.
Oligonucleotide Analysis in Pharmaceutical Quality Control
January 14th 2025Melting point determination using ultraviolet-visible (UV-Vis) spectrophotometry can be used as a sequence-specific method for identifying therapeutic oligonucleotides in pharmaceutical quality control. This method offers a simple, highly selective approach to differentiate between isomers and ensure the integrity of oligonucleotide active pharmaceutical ingredients (APIs) and drug products.
