Streamlined Workflows for N-Glycan Analysis of Biotherapeuticss Using Agilent AdvanceBio Gly-X Instant PC and 2-AB Express Sample Preparation with LC/FLD/MS
This Application Note describes the preparation and analysis of released N-glycans from biotherapeutic glycoproteins using InstantPC and 2-aminobenzamide (2-AB) labels.
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New Strategies for a Better Glycosylation Profile
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Glycan analysis provides key information on critical quality attributes that could affect stability, safety and efficacy of a protein therapeutic. Specific needs for understanding the glycosylation profiles change throughout the drug development process, but the requirement for high-resolution glycan information remains the same and is essential to help ensure product quality.
