Purification of Antibodies with Hydrophobic Anion Exchange Resin
A new hydrophobic anion exchange mixed-mode resin has been developed to overcome existing challenges in antibody purification. Described here are two case studies on the purification of an acidic and a basic antibody in bind-elute and flow-through modes. The results demonstrate the ability of this resin to improve process productivity and economy.
New Strategies for a Better Glycosylation Profile
January 22nd 2025Glycan analysis provides key information on critical quality attributes that could affect stability, safety and efficacy of a protein therapeutic. Specific needs for understanding the glycosylation profiles change throughout the drug development process, but the requirement for high-resolution glycan information remains the same and is essential to help ensure product quality.
