Celgene to Acquire Abraxis
In an effort to strengthen its oncology pipeline, Celgene Corporation (Summit, NJ) will acquire California-based Abraxis BioScience Inc. for approximately $2.9 billion in stock and cash. The transaction adds Abraxane, an injectable drug that is approved as a treatment for metastatic breast cancer and is being studied in a number of other solid tumors including lung and pancreatic cancers, to Celgene’s existing portfolio of cancer drugs.
Under the terms of the merger agreement, each share of Abraxis BioScience common stock will be converted into the right to receive an upfront payment of $58 in cash and 0.2617 shares of Celgene common stock. Each share will also receive one tradeable contingent value right, which entitles its holder to receive payments for future regulatory milestones and commercial royalties. The acquisition of Abraxis is expected to close in the fourth quarter of 2010.
Celgene may explore the application of Abraxane’s “nab” technology to other compounds. Celgene’s two top-selling drugs are Revlimid and Thalomid, which are treatments for multiple myeloma. In January, Celgene acquired Gloucester Pharmaceuticals Inc., gaining the marketed lymphoma drug Istodax.
Mastering Antibody-Drug Conjugates
December 19th 2024In this episode, we explore BIOVECTRA’s capabilities in antibody-drug conjugate (ADC) manufacturing, from complex conjugation chemistry to synthesis of highly potent payloads. We’ll also showcase how BIOVECTRA’s extensive experience in complex chemistries and specialized small molecule manufacturing gives them a unique perspective, strengthening their approach to ADC production and ensuring clients receive custom solutions across all project stages.
Filter Sizing for Process Optimization in Life Sciences Sterile Filtration
April 24th 2025Bench-scale filterability studies play a critical role in optimizing sterile filtration in biopharmaceutical manufacturing. By guiding the selection and sizing of filters, these studies help streamline processes, improve scalability, and reduce costs. Through data-driven case studies, this paper highlights how the strategic use of pre-filters and membrane materials can maximize throughput and minimize filter fouling.
VERAXA and Voyager to Create Combined Business for Advancing Pipeline of Next-Gen Cancer Therapies
April 23rd 2025The proposed business combination would create a publicly traded, clinical-stage biopharmaceutical company that will focus on developing a pipeline of next-generation cancer therapies.