BioPharm International Digital Edition, June 2010 Supplement (PDF)
Advances in Fermentation & Cell Culture: The Keys to Upstream Productivity
Developing an Automatically Controlled Feeding Process in an E. coli Fermentation Process for Recombinant Protein Production
An exponential feeding strategy coupled with automation doubled protein yields while reducing fermentation time by 25%.
Using Information Technology to Enhance Upstream Productivity
Two case studies show how advanced information technologies make process development more efficient.
Best Practices for Microbial Fermenter Equipment Characterization
Wet testing of microbial fermenters allows for a greater understanding of the equipment's capabilities.
Balancing Media Development with Patient Safety
The quest for increased productivity and better process control combined with patient safety has encouraged biopharmaceutical companies to use chemically defined media for cell culture.
Partial Replacement of Chemically Defined Media with Plant-Derived Protein Hydrolysates
Plant-derived hydrolysates can be used as valuable and practical tools to improve cell culture performance.
