Lauren Lavelle

As COVID-19 continues to spread, industry leaders are banding together to stop the disease in its tracks.

Recent CDMO partnerships include COVID-19 collaborations, manufacturing partnerships, service agreements, and a strategic alliance expansion.

Growth in cell and gene therapies puts pressure on the raw materials supply chain.

The Altrui Foundation is a non-profit organization that serves as a center point between manufacturers of unused medications and the charitable organizations that seek them.

New advancements in lab data management technologies include devices with a fully integrated SDMS, a cloud-based and an online ELN, an ELN featuring a virtual assistant, and updated LIMS software.

The latest advances in downstream technologies include sterile disconnects for single-use manufacturing systems, ligand technologies for purifying RNA and for COVID-19 vaccines, and an automated perfusion system.

Working with incubators can provide cell and gene therapy developers with more opportunities.

The complexity of biologics and the use of new technologies present challenges for complying with CGMPs.

Having remote operations in place is crucial to maintaining good automation practices.

The latest advances in upstream technologies include single-use equipment and a protein analyzer for titer monitoring, as well as new plasmid DNA manufacturing capability.

The latest advances in downstream technologies include stainless-steel liquid chromatography columns, sensing and control units for hygienic valves, a wettable phase for separation and purification, a buffer delivery platform, and a new filter integrity tester.

The latest advances in process chromatography include pre-packed chromatography columns, process characterization kits, fast protein liquid chromatography systems, and mixed-mode chromatography resins.