BioPharm International
October 02, 2009
Peer-Reviewed Research
2009 Supplement
7
The future of therapeutic MAbs lies in the development of economically feasible downstream processes.
October 02, 2009
Peer-Reviewed Research
2009 Supplement
7
A membrane adsorber in retention mode can be used efficiently in a commercial antibody manufacturing process.
October 02, 2009
Peer-Reviewed Research
2009 Supplement
7
Precipitation prior to capture chromatography offers a simple, robust, and economical method to remove CHO host cell proteins and DNA.
October 02, 2009
Peer-Reviewed Research
2009 Supplement
7
This alternative to column chromatography is suitable for flow-through as well as bind-and-elute purification operations.
October 02, 2009
Peer-Reviewed Research
2009 Supplement
7
New techniques can overcome bottlenecks in existing facilities.
October 02, 2009
Peer-Reviewed Research
2009 Supplement
7
STIC allows polishing to be carried out without an interstitial dilution step, which reduces process time and avoids additional buffer preparation and hold steps.
October 02, 2009
Peer-Reviewed Research
2009 Supplement
7
A purification scheme to maximize the efficiency of the purification process and product purity while minimizing the development time for early-phase therapeutic antibodies.